Archive for ◊ January, 2012 ◊

Ultram relieves pain but not completely
Author:
• Sunday, January 29th, 2012

There’s a rumor going round the town that pain is a bad thing and should be eliminated at all costs. Big Boss Pharma has been lining up all its big guns and, no matter what level of pain you may be experiencing, there’s a pill with your name on it, assuming you get a prescription, of course. You may therefore look at the headline here and be a little surprised. How on Earth can anyone think pain is a good thing? Well, let’s go back to basics. Darwin, that inconvenient man who thinks we all evolved rather than were created, argued only the best-adapted species survived. When it comes to survival, the animal needs to know when it’s under attack. If it’s injured, it decides whether to fight or flee. So pain is a vital signal to the brain. It warns when the body is injured. We benefitted from that when we were less well-developed. Today, it’s still useful to know if we have accidentally injured ourselves or just picked up something too hot to hold.

The modern response is to seek medical assistance and then we complain when the pain message continues. So let’s move medical science a few years into the future. Rather in the same way we can switch off the burglar alarm when we know someone has broken into our home, a researcher develops a magic pill to switch off pain. It changes the brain’s chemistry so we are no longer aware of any pain. Would you take it? Before you rush to an answer, the scientist confirms this is an all or nothing pill. Either you feel pain or you do not. We will have to go into real science fiction to arrive at a treatment that only switches off the pain messages from the injured part of the body. In theory, it should be possible to neutralize the pain by interrupting the nervous system at key junctions, e.g. where an arm or leg joins the body. Unfortunately, this also risks paralyzing the arm or leg.

Anyway, back to the question. Would you take a pill to switch off pain? It would mean you would not know if you were damaging any other part of your body. Suppose you drink something that’s burning your tongue, or slip and make your existing injury worse. You would not know to stop drinking or seek further medical treatment. Completely turning off pain is dangerous unless you lie perfectly still and take no physical risks. Even then, you would not know if you were getting the first pain symptoms of a heart attack or warning indications of any other disease. The present situation is safer because a drug like Ultram simply reduces the intensity of the current pain. You can still feel if any other part of your body is injured or you are affected by some other disease or disorder.

In Europe, the trend is to teach people pain management techniques so they can achieve a good quality of life without having to rely on painkillers. This does not deny a role for drugs like Ultram. They will still be used for short-term relief should pain flare up. The hope is people can cope without risking dependence on drugs.

Category: News  | Tags:  | Leave a Comment
How Propecia was developed
Author:
• Thursday, January 19th, 2012

How Propecia was developed

Humble beginnings

Propecia first hit the market as a drug intended for treatment of enlarged prostate glands in men, back in 1992. It was invented as a result of observations based on sexual development observed in children as they matured. In some boys, a significantly smaller prostate and absence of male pattern baldness was found upon reaching adulthood. Under further examination, hormonal compounds were then discovered that, when isolated, helped with prostate enlargement. It was later noted that patients undergoing treatment also showed improvement in their hair loss. These observations eventually led to the development of the first-ever successful treatment for male pattern baldness.

Propecia FDA approval

Although the FDA approved the drug initially in 1992, it was specifically designated for use in treating enlarged prostates. However, they officially endorsed its use for effectively treating hair loss a few years later, in 1997. Since then, propecia is far and away the most effective prescription drug treatment available for stopping the procession of male pattern baldness, and also hair loss due to other causes. Unfortunately, it is only used for male hair loss, and not for female.

Alternative Prescription Treatments

There are only a handful of other prescription treatment options for male pattern baldness. One of these, while showing signs of effectiveness in other countries, has not been yet approved for safe or effective use in the United States. Other treatment options that have been tried include a cream that is applied directly to the scalp. This was originally intended as treatment for psoriasis of the scalp. It has shown some improvement in cases of very mild hair loss, but has not been officially approved for use in treating baldness by the FDA. Another treatment sometimes prescribed comes in the form of cortisone shots. These are injected on a monthly basis, directly into the scalp. Cortisone pills are also sometimes used, but they are not always effective and can have various harmful side effects. While these treatments also show some signs of effectiveness, many doctors are not comfortable suggesting using cortisone in cases of long-term use.

Propecia vs. Over-the-Counters

Since hair loss affects so many people, and does not have very many choices for effective treatment, a variety of creams, pills, and powders have sprung up in an attempt to entice the buyer. Since none of these products has ever undergone systematic testing either for safety or effectiveness, their success rates is largely anecdotal, and not necessarily reliable. propecia is truly the best option for those seeking effective treatment for their hair loss.

Category: News  | Tags: ,  | Leave a Comment
A good idea?
Author:
• Monday, January 16th, 2012

A British doctor is acting the role of a pioneer. By specialism, he’s a cardiologist so one of his routine tasks is to insert a stent into blood vessels in the chest leading into and out of the heart. A stent is a cleverly designed support tube that’s inserted into a blood vessel affected by artherosclerosis. This is a disease caused by eating too much carbohydrate. Additional platelets precipitate out of the blood and build up on the walls of the vessels. The first symptom is a rise in blood pressure, which is caused when the deposits narrow the vessel. One day, the Brit had an inspiration. Since one of the more common reasons for erectile dysfunction is artherosclerosis affecting the penile artery, would it help to insert a stent into that artery?

In such situations, there’s no point in asking the question unless you’re prepared to find out the answer. When he mentioned the experiment to some of the men attending the urology department, he had a lot of volunteers. If men delay treatment, the hardening of the artery is not reversible. So, no matter which erectile dysfunction drug you take, it’s not going to help. Erections only return when the artery can dilate properly. Doctors estimate there’s a critical moment when the blockage of the artery reaches 70%. That’s the cut-off for the erectile dysfunction drugs to work. It’s still possible to force an erection using a vacuum pump but the pump is clumsy and kills all spontaneity. So, for all practical purposes, about 30% of men will find their erectile dysfunction a permanent condition.

The test to discover whether the surgery will be effective is simple. A dye is injected and its progress monitored by X-ray. If it shows seriously reduced flow through the penile artery, the procedure is likely to help. There’s no need for a full anesthetic. The stent is inserted through the arteries in the groin. Once in place, the results have been impressive with men reporting no residual discomfort and, when stimulated, a hard erection up to twelve months after the procedure.

This surgery is not for everyone. Its success depends on a blockage at just the right point in the penile artery. Even then, there may be no improvement if the man has other muscular problems. Nevertheless, it’s an interesting idea and this surgeon has a growing queue of men waiting for the operation. Now to put this in context, let’s go back to basics. No one with any sense should allow the problem to become this severe before seeking help. If you are overweight and eat an unhealthy diet, treat the first signs of erectile dysfunction as a warning of serious problems. Have all the cardiovascular tests done to see whether you have early symptoms of artherosclerosis. If the diagnosis is confirmed, the drugs are available to reduce the metabolic dangers. Levitra for the erectile dysfunction will keep the sex enjoyable while you change your diet and begin a course of gentle physical exercise. But if you refuse to go through the tests or then refuse to make the lifestyle changes, the Levitra will keep the erections going for a while but, sooner or later, the erections will disappear never to return. This will blight your life, so it’s worth avoiding.

Category: News  | Tags:  | Leave a Comment
Why does advertising work?
Author:
• Sunday, January 01st, 2012

Here’s a number to start us off. Marketers spend about $70 billion a year on TV ads! That’s a lot of cash! But companies out to make a profit would not spend that much on ads unless there was good evidence they work. Except, what is it, exactly, that ads do? The myth is marketers want you to buy a product the first chance you have. It’s like the old movie joke about cinemas so desperate to boost sales of ice cream, they would turn up the heating during the first feature and trigger a rush for something cool by showing an ad at the start of the intermission. The majority of ads are designed to sit in your memory. It’s like the Geico ads with the caveman or, more specifically the pig who cries wee all the way home.

There’s good evidence that hard selling techniques create a negative impression. We all take some pride in our ability to resist. So the aim is to build up brand awareness. Over time, we associate each brand with the product or service. The challenge is then to convert these memories of an amusing ad or catchy slogan into action. After all, why go to all the trouble of planting the seed if you don’t then go on to encourage people to buy later on? Except, marketers have no real control over our actions. Most of us use the ad break to make a quick cup of coffee or empty the bladder of all the coffee we’ve drunk over the evening. No one ever sits down to watch the ads. All we do is catch glimpses of the ads in passing. This constant repetition is like drip-feed, slowly building up brand awareness so that, if we’re making a decision on which product or service to buy at some time in the future, we might buy the one with the most memorable ad.

Creativity is what sells brand awareness. We remember the funny ads, or the strange ads, or the visually interesting ads, or the ads with the best music tracks. So now imagine you’re going to be paid a big chunk of cash to create a memorable ad for an erectile dysfunction drug. If you’re selling a car, you can show it accelerating from 0 to 60 in five seconds. Imagine the response of the television stations if you showed the pill producing an erection in record time. That would really test the First Amendment. So you need to sneak up on people and, hopefully, slip past their defenses before they know you’re there.

Have you seen that ad for Cialis? The one where the couple end up in separate tubs. This is one of the weird ones, isn’t it? Everyone would expect to see the happy couple gazing into each other’s eyes, perhaps hugging or, at least, holding hands. So what’s with the separate washing arrangements? Except the moment you ask the question, you’re hooked. It’s memorable because it makes you think. Like the woman driving the pig home. Her long-suffering expression says everything that needs to be said. Repeat the ad often enough and people associate the ad with the brand name. So remember Cialis really can give you 15% more on your erections.

Category: News  | Tags:  | Leave a Comment