There is one more reason to quit smoking. Researchers from Leiden University Medical Center in the Netherlands report that the habit substantially increases one’s risk of developing a common form of skin cancer called squamous cell carcinoma.
“Everybody realizes that sun exposure is a risk for skin cancer, but almost no one knows that smoking is also an important, and independent, risk factor,” according to study co-author, Jan Nico Bouwes Bavinck, MD.
Skin cancer is the most common form of cancer in the U.S., with approximately 1.2 million new cases diagnosed every year. Malignant melanoma is the most deadly form of the disease, but it accounts for only about 5% of all cases. Much more common are the nonmelanoma skin cancers, the group that includes squamous cell carcinoma.
Squamous cell carcinoma is the second-most common type of skin cancer in the U.S, accounting for approximately 16% of all skin cancers. Although the cure rate for squamous cell carcinoma is about 95%, it still kills about 2,000 Americans each year.
Skin expert Robert M. Tornambe, MD, tells that the study results are somewhat weakened because the Dutch investigators looked specifically at the smoking habits of people who already had skin cancer, instead of designing a study to predict who would develop skin cancer in the future. Still, the findings are convincing enough to offer another good reason to stop smoking, he says — or not to start at all.
“Besides all the other effects of smoking, there’s a good chance that you have a higher risk of getting skin cancer, says Tornambe, chief of plastic surgery at Cabrini Medical Center in New York City. “More importantly, the treatment can be complicated by smoking as well” — because smoking constricts blood vessels and slows healing.
For the study, the Leiden University investigators looked at the smoking history of 740 people with skin cancer, including 161 people with squamous cell carcinoma. For comparison, they also collected similar information on 386 individuals with no history of skin cancer.
The researchers found that smokers were 3.3 times more likely and ex-smokers 1.9 times more likely to develop squamous cell carcinoma. As the number of cigarettes and pipes smoked increased, so did the risk of cancer. Smoking did not appear to increase the risk of developing the other types of skin cancer examined, and smoking cigars did not appear to increase the risk of any type of skin cancer. The study is published in the January 2001 issue of the Journal of Clinical Oncology.
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